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  Whole genome sequences of a male and female supercentenarian, ages greater than 114 years 

  Sebastiani, Paola; Riva, Alberto; Montano, Monty; Pham, Phillip; Torkamani, Ali; Scherba, Eugene; Benson, Gary; Milton, Jacqueline N.; Baldwin, Clinton T.; Andersen, Stacy; Schork, Nicholas J.; Steinberg, Martin H.; Perls, Thomas T. (2011)

  Supercentenarians (age 110+ years old) generally delay or escape age-related diseases and disability well beyond the age of 100 and this exceptional survival is likely to be influenced by a genetic predisposition that ...
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  Design of the WHIP-PD study: a phase II, twelve-month, dual-site, randomized controlled trial evaluating the effects of a cognitive-behavioral approach for promoting enhanced walking activity using mobile health technology in people with Parkinson-disease 

  Rawson, K.S.; Cavanaugh, James T.; Colon-Semenza, Cristina; DeAngelis, T.; Duncan, R.P.; Fulford, Daniel; LaValley, Michael P.; Mazzoni, P.; Nordahl, T.; Quintiliani, Lisa M.; Saint-Hilaire, Marie-Helene; Thomas, Cathi A.; Earhart, G.M.; Ellis, Theresa D. (2020-04-20)

  BACKGROUND: Parkinson disease (PD) is a debilitating and chronic neurodegenerative disease resulting in ambulation difficulties. Natural walking activity often declines early in disease progression despite the relative ...
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  Long-term yogurt consumption and risk of incident hypertension in adults 

  Buendia, Justin Rene; Li, Yanping; Hu, Frank B.; Cabral, Howard J.; Bradlee, M. Loring; Quatromoni, Paula A.; Singer, Martha R.; Curhar, Gary C.; Moore, Lynn L. (LIPPINCOTT WILLIAMS & WILKINS, 2018-08-01)
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  Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model 

  Tagge, Chad A.; Fisher, Andrew M.; Minaeva, Olga V.; Gaudreau-Balderrama, Amanda; Moncaster, Juliet A.; Zhang, Xiao-Lei; Wojnarowicz, Mark W.; Casey, Noel; Lu, Haiyan; Kokiko-Cochran, Olga N.; Saman, Sudad; Ericsson, Maria; Onos, Kristen D.; Veksler, Ronel; Senatorov, Vladimir V.; Kondo, Asami; Zhou, Xiao Z.; Miry, Omid; Vose, Linnea R.; Gopaul, Katisha R.; Upreti, Chirag; Nowinski, Christopher J.; Cantu, Robert C.; Alvarez, Victor E.; Hildebrandt, Audrey M.; Franz, Erich S.; Konrad, Janusz; Hamilton, James A.; Hua, Ning; Tripodis, Yorghos; Anderson, Andrew T.; Howell, Gareth R.; Kaufer, Daniela; Hall, Garth F.; Lu, Kun P.; Ransohoff, Richard M.; Cleveland, Robin Olav; Kowall, Neil W.; Stein, Thor D.; Lamb, Bruce T.; Huber, Bertrand R.; Moss, William C.; Friedman, Alon; Stanton, Patric K.; McKee, Ann C.; Goldstein, Lee E. (OXFORD UNIV PRESS, 2018-02-01)

  The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic encephalopathy, and the relationships between these disorders, are poorly understood. We examined post-mortem brains from teenage athletes ...
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  A Three-Stage Approach for Genome-Wide Association Studies with Family Data for Quantitative Traits 

  Chen, Ming-Huei; Larson, Martin G.; Hsu, Yi-Hsiang; Peloso, Gina M.; Guo, Chao-Yu; Fox, Caroline S.; Atwood, Larry D.; Yang, Qiong (BioMed Central, 2010-5-14)

  BACKGROUND. Genome-wide association (GWA) studies that use population-based association approaches may identify spurious associations in the presence of population admixture. In this paper, we propose a novel three-stage ...
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  Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six loci influencing serum magnesium levels 

  Meyer, Tamra E.; Verwoert, Germaine C.; Hwang, Shih-Jen; Glazer, Nicole L.; Smith, Albert V.; Van Rooij, Frank J. A.; Ehret, Georg B.; Boerwinkle, Eric; Felix, Janine F.; Leak, Tennille S.; Harris, Tamara B.; Yang, Qiong; Dehghan, Abbas; Aspelund, Thor; Katz, Ronit; Homuth, Georg; Kocher, Thomas; Rettig, Rainer; Ried, Janina S.; Gieger, Christian; Prucha, Hanna; Pfeufer, Arne; Meitinger, Thomas; Coresh, Josef; Hofman, Albert; Sarnak, Mark J.; Chen, Yii-Der Ida; Uitterlinden, André G.; Chakravarti, Aravinda; Psaty, Bruce M.; Van Duijn, Cornelia M.; Kao, W. H. Linda; Witteman, Jacqueline C. M.; Gudnason, Vilmundur; Siscovick, David S.; Fox, Caroline S.; Köttgen, Anna (Public Library of Science, 2010-8-5)

  Magnesium, potassium, and sodium, cations commonly measured in serum, are involved in many physiological processes including energy metabolism, nerve and muscle function, signal transduction, and fluid and blood pressure ...
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  Automated MRI Measures Identify Individuals with Mild Cognitive Impairment and Alzheimer's Disease* 

  Desikan, Rahul S.; Cabral, Howard J.; Hess, Christopher P.; Dillon, William P.; Glastonbury, Christine M.; Weiner, Michael W.; Schmansky, Nicholas J.; Greve, Douglas N.; Salat, David H.; Buckner, Randy L.; Fischl, Bruce (Oxford University Press, 2009-5-21)

  Mild cognitive impairment can represent a transitional state between normal ageing and Alzheimer's disease. Non-invasive diagnostic methods are needed to identify mild cognitive impairment individuals for early therapeutic ...
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  Genetic Analysis Workshop 15: Gene Expression Analysis and Approaches to Detecting Multiple Functional Loci 

  Cordell, Heather J.; de Andrade, Mariza; Babron, Marie-Claude; Bartlett, Christopher W.; Beyene, Joseph; Bickeböller, Heike; Culverhouse, Robert; Cupples, L. Adrienne; Daw, E. Warwick; Dupuis, Josée; Falk, Catherine T.; Ghosh, Saurabh; Goddard, Katrina A.; Goode, Ellen L.; Hauser, Elizabeth R.; Martin, Lisa J.; Martinez, Maria; North, Kari E.; Saccone, Nancy L.; Schmidt, Silke; Tapper, William; Thomas, Duncan; Tritchler, David; Vieland, Veronica J.; Wijsman, Ellen M.; Wilcox, Marsha A.; Witte, John S.; Yang, Qiong; Ziegler, Andreas; Almasy, Laura; MacCluer, Jean W. (BioMed Central, 2007-12-18)
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  Joint Modeling of Linkage and Association Using Affected Sib-Pair Data 

  Chen, Ming-Huei; Cui, Jing; Guo, Chao-Yu; Cupples, L. Adrienne; Van Eerdewegh, Paul; Dupuis, Josée; Yang, Qiong (BioMed Central, 2007-12-18)

  There has been a growing interest in developing strategies for identifying single-nucleotide polymorphisms (SNPs) that explain a linkage signal by joint modeling of linkage and association. We compare several existing ...
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  Comparisons of Case-Selection Approaches Based on Allele Sharing and/or Disease Severity Index: Application to the GAW14 Simulated Data 

  Liu, Chunyu; Cupples, L. Adrienne; Dupuis, Josée (BioMed Central, 2005-12-30)

  For mapping complex disease traits, linkage studies are often followed by a case-control association strategy in order to identify disease-associated genes/single-nucleotide polymorphisms (SNPs). Substantial efforts are ...

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