MED: Neurology Scholarly Works
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URI: http://hdl.handle.net/2144/2430
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COVID-19 shines a light on health inequities in communities of color: a youth-driven photovoice inquiry
(Wiley, 2022-09)This manuscript reports on a youth-driven health assessment engaging youth of color in identifying community health priorities during the coronavirus disease 2019 (COVID-19) pandemic. Photovoice, a participatory visual ... -
Dissecting the mechanism of the nonheme iron endoperoxidase FtmOx1 using substrate analogues
(American Chemical Society (ACS), 2022-07-25)FtmOx1 is a nonheme iron (NHFe) endoperoxidase, catalyzing three disparate reactions, endoperoxidation, alcohol dehydrogenation, and dealkylation, under in vitro conditions; the diversity complicates its mechanistic studies. ... -
Illicit drug use and cerebral microbleeds in stroke and transient ischemic attack patients
(Stroke, 2019-01-30)Background: Cerebral microbleeds (CMB) signal cerebral small vessel disease and are associated with ischemic stroke (IS) incidence, recurrence, and complications. While illicit drug use (IDU) is associated with cerebral ... -
Frontal Brain Dysfunction in Alcoholism with and without Antisocial Personality Disorder
(Dove Medical Press, 2009-06-10)Alcoholism and antisocial personality disorder (ASPD) often are comorbid conditions. Alcoholics, as well as nonalcoholic individuals with ASPD, exhibit behaviors associated with prefrontal brain dysfunction such as increased ... -
Test of Variables of Attention (TOVA) as a Predictor of Early Attention Complaints, an Antecedent to Dementia
(Dove Medical Press, 2010-10-15)The goal of this study was to determine if impairments detected by the test of variables of attention (TOVA) may be used to predict early attention complaints and memory impairments accurately in a clinical setting. We ... -
On the Analysis of Genome-Wide Association Studies in Family-Based Designs: A Universal, Robust Analysis Approach and an Application to Four Genome-Wide Association Studies
(Public Library of Science, 2009-11-26)For genome-wide association studies in family-based designs, we propose a new, universally applicable approach. The new test statistic exploits all available information about the association, while, by virtue of its design, ... -
Attention-Deficit-Hyperactivity Disorder and Reward Deficiency Syndrome
(Dove Medical Press, 2008)Molecular genetic studies have identified several genes that may mediate susceptibility to attention deficit hyperactivity disorder (ADHD). A consensus of the literature suggests that when there is a dysfunction in the ... -
Tetrabenazine: The First Approved Drug for the Treatment of Chorea in US Patients with Huntington Disease
(Dove Medical Press, 2010-10-05)Huntington disease (HD) is a dominantly inherited progressive neurological disease characterized by chorea, an involuntary brief movement that tends to flow between body regions. HD is typically diagnosed based on clinical ... -
A Three-Stage Approach for Genome-Wide Association Studies with Family Data for Quantitative Traits
(BioMed Central, 2010-5-14)BACKGROUND. Genome-wide association (GWA) studies that use population-based association approaches may identify spurious associations in the presence of population admixture. In this paper, we propose a novel three-stage ... -
Comparisons of Case-Selection Approaches Based on Allele Sharing and/or Disease Severity Index: Application to the GAW14 Simulated Data
(BioMed Central, 2005-12-30)For mapping complex disease traits, linkage studies are often followed by a case-control association strategy in order to identify disease-associated genes/single-nucleotide polymorphisms (SNPs). Substantial efforts are ...
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