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  Neuroprotective effects of carnitinoid compounds in rodent cellular and in vivo models of mitochondrial complex I dysfunction 

  Steliou, Kosta (Mesford Publisher Inc, 2019-03-13)

  Rotenone-mediated mitochondrial complex I inhibition was used to model Parkinson’s disease-like syndrome in Lewis rats. Tyrosine hydroxylase immunolabeling demonstrated a decrease in the number of dopaminergic neurons as ...
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  A new approach to treating neurodegenerative otologic disorders 

  Moos, Walter H.; Faller, Douglas V.; Glavas, Ioannis P.; Harpp, David N.; Irwin, Michael H.; Kanara, Iphigenia; Pinkert, Carl A.; Powers, Whitney R.; Steliou, Kosta; Vavvas, Demetrios G.; Kodukula, Krishna (2018)

  Hearing loss, the most common neurological disorder and the fourth leading cause of years lived with disability, can have profound effects on quality of life. The impact of this "invisible disability," with significant ...
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  Gut microbiota and salivary diagnostics: the mouth is salivating to tell us something. 

  Kodukula, Krishna; Faller, Douglas V.; Harpp, David N.; Kanara, Iphigenia; Pernokas, Julie; Pernokas, Mark; Powers, Whitney R.; Soukos, Nikolaos S.; Steliou, Kosta; Moos, Walter H. (2017)

  The microbiome of the human body represents a symbiosis of microbial networks spanning multiple organ systems. Bacteria predominantly represent the diversity of human microbiota, but not to be forgotten are fungi, viruses, ...
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  Epigenetic treatment of neurodegenerative ophthalmic disorders: an eye toward the future. 

  Moos, Walter H.; Faller, Douglas V.; Glavas, Ioannis P.; Harpp, David N.; Irwin, Michael H.; Kanara, Iphigenia; Pinkert, Carl A.; Powers, Whitney R.; Steliou, Kosta; Vavvas, Demetrios G.; Kodukula, Krishna (2017)

  Eye disease is one of the primary medical conditions that requires attention and therapeutic intervention in ageing populations worldwide. Further, the global burden of diabetes and obesity, along with heart disease, all ...
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  Microbiota and neurological disorders: a gut feeling. 

  Moos, Walter H.; Faller, Douglas V.; Harpp, David N.; Kanara, Iphigenia; Pernokas, Julie; Powers, Whitney R.; Steliou, Kosta (2016)

  In the past century, noncommunicable diseases have surpassed infectious diseases as the principal cause of sickness and death, worldwide. Trillions of commensal microbes live in and on our body, and constitute the human ...
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  A Computational Approach for Deciphering the Organization of Glycosaminoglycans 

  Spencer, Jean L.; Bernanke, Joel A.; Buczek-Thomas, Jo Ann; Nugent, Matthew A. (Public Library of Science, 2010-2-23)

  BACKGROUND. Increasing evidence has revealed important roles for complex glycans as mediators of normal and pathological processes. Glycosaminoglycans are a class of glycans that bind and regulate the function of a wide ...
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  Giardia Cyst Wall Protein 1 Is a Lectin That Binds to Curled Fibrils of the GalNAc Homopolymer 

  Chatterjee, Aparajita; Carpentieri, Andrea; Ratner, Daniel M.; Bullitt, Esther; Costello, Catherine E.; Robbins, Phillips W.; Samuelson, John (Public Library of Science, 2010-8-19)

  The infectious and diagnostic stage of Giardia lamblia (also known as G. intestinalis or G. duodenalis) is the cyst. The Giardia cyst wall contains fibrils of a unique β-1,3-linked N-acetylgalactosamine (GalNAc) homopolymer ...
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  Hematopoietic Gene Promoters Subjected to a Group-Combinatorial Study of DNA Samples: Identification of a Megakaryocytic Selective DNA Signature 

  Hazony, Yehonathan; Lu, Jun; St. Hilaire, Cynthia; Ravid, Katya (Oxford University Press, 2006-08-26)

  Identification of common sub-sequences for a group of functionally related DNA sequences can shed light on the role of such elements in cell-specific gene expression. In the megakaryocytic lineage, no one single unique ...
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  Tri-Nucleotide Receptors Play a Critical Role in Epithelial Cell Wound Repair 

  Weinger, Ilene; Klepeis, Veronica E.; Trinkaus-Randall, Vickery (Springer Netherlands, 2005-7-29)

  The cornea plays a major role in the refraction of light to the retina. Therefore, the integrity and transparency of the corneal epithelium are critical to vision. Following injury, a combination of rapid signal transduction ...
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  Inhibition of Influenza M2-Induced Cell Death Alleviates Its Negative Contribution to Vaccination Efficiency 

  Ilyinskii, Petr O.; Gambaryan, Alexandra S.; Meriin, Anatoli B.; Gabai, Vladimir; Kartashov, Alex; Thoidis, Galini; Shneider, Alexander M. (Public Library of Science, 2008-1-16)

  The effectiveness of recombinant vaccines encoding full-length M2 protein of influenza virus or its ectodomain (M2e) have previously been tested in a number of models with varying degrees of success. Recently, we reported ...

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