The asymmetric aldol reaction
dc.contributor.author | Mulcahy, Seann P. | en_US |
dc.date.accessioned | 2012-01-03T18:04:11Z | |
dc.date.available | 2012-01-03T18:04:11Z | |
dc.date.issued | 2012-01-03 | |
dc.identifier.uri | https://hdl.handle.net/2144/2684 | |
dc.description | This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License: http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
dc.description.abstract | A convenient multi-week experiment that results in the formation of two new stereocenters starting from enantiopure norephedrine as the chiral auxiliary. This experiment uses a variety of purification techniques, including distillation, recrystallization, and column chromatography and is a useful extension of classroom topics. Students can be introduced to transition state modeling, COSY spectroscopy, Hammond postulate, and asymmetric induction. | en_US |
dc.language.iso | en_US | |
dc.subject | Aldol reaction | en_US |
dc.subject | Chromatography | en_US |
dc.subject | Hammond postulate | en_US |
dc.subject | Distillation | en_US |
dc.subject | Recrystallization | en_US |
dc.subject | Asymmetric induction | en_US |
dc.subject | Stereochemistry | en_US |
dc.title | The asymmetric aldol reaction | en_US |
dc.type | Other | en_US |
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