Department of Neurosurgery
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Capzb2 Interacts with β-Tubulin to Regulate Growth Cone Morphology and Neurite Outgrowth
(Public Library of Science, 2009-10-6)An actin regulatory protein unexpectedly also controls microtubule polymerization during the formation and maintenance of cellular outgrowths in neurons. Capping protein (CP) is a heterodimer that regulates actin assembly ... -
Control of Activating Transcription Factor 4 (ATF4) Persistence by Multisite Phosphorylation Impacts Cell Cycle Progression and Neurogenesis*
(American Society for Biochemistry and Molecular Biology, 2010-8-19)Organogenesis is a highly integrated process with a fundamental requirement for precise cell cycle control. Mechanistically, the cell cycle is composed of transitions and thresholds that are controlled by coordinated ... -
Cerebral Collateral Circulation in Carotid Artery Disease
(Bentham Science Publishers Ltd., 2011-12-29)Carotid artery disease is common and increases the risk of stroke. However, there is wide variability on the severity of clinical manifestations of carotid disease, ranging from asymptomatic to fatal stroke. The collateral ...